(S)-(+)-Mosher's acid chloride

Names

[ Name ]:
(S)-(+)-Mosher's acid chloride

[Synonym ]:
(-)-Mosher's Acid Chloride
(-)-α-Methoxy-α-(trifluoroMethyl)phenylacetyl Chloride
MFCD00067105
(S)-(+)-MTPA-Cl
Benzeneacetyl chloride, α-methoxy-α-(trifluoromethyl)-, (αS)-
Mosher's acid chloride
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride
(2S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoyl chloride
(S)-Mosher's acid chloride
(-)-MTPA-Cl
(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
213.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₈ClF₃O₂

[ Molecular Weight ]:
252.617

[ Flash Point ]:
90.0±0.0 °C

[ Exact Mass ]:
252.016495

[ PSA ]:
26.30000

[ LogP ]:
5.03

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.464

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C

[ Risk Phrases ]:
34

[ Safety Phrases ]:
26-27-36/37/39-45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8.0

[ HS Code ]:
2918990090

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

High-performance liquid chromatographic resolution of enantiomers of 1-phenyl-2-aminopropanes (amphetamines) with four chiral reagents.

J. Chromatogr. A. 307 , 335, (1984)

High-performance liquid chromatography (HPLC) was employed for resolution of enantiomers of chiral ring-substituted 1-phenyl-2- aminopropanes (amphetamines) and 1-phenylethylamine following derivatiza...

Mosher ester analysis for the determination of absolute configuration of stereogenic (chiral) carbinol carbons.

Nat. Protoc. 2 , 2451-2458, (2007)

This protocol details the most commonly used nuclear magnetic resonance (NMR)-based method for deducing the configuration of otherwise unknown stereogenic, secondary carbinol (alcohol) centers (R1R2CH...

J.A. Dale, H.S. Mosher

J. Am. Chem. Soc. 95 , 512, (1973)