SMAP-29

Names

[ Name ]:
SMAP-29

Biological Activity

[Description]:

SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: bacterial; fungal[1]

[References]

[1]. B Skerlavaj, et al. SMAP-29: a potent antibacterial and antifungal peptide from sheep leukocytes. FEBS Lett. 1999 Dec 10;463(1-2):58-62.

[2]. Rachel C Anderson, et al.Antimicrobial activity and bacterial-membrane interaction of ovine-derived cathelicidins. Antimicrob Agents Chemother

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄₆H₂₆₀N₅₂O₃₂

[ Molecular Weight ]:
3256.02

SMAP-29

Names

Biological Activity

Chemical & Physical Properties

Related Compounds