5’-O-TBDPS-5-methyl-2,2’-anhydrouridine

Names

[ CAS No. ]:
171763-19-2

[ Name ]:
5’-O-TBDPS-5-methyl-2,2’-anhydrouridine

Biological Activity

[Description]:

5’-O-TBDPS-5-methyl-2,2’-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H30N2O5Si

[ Molecular Weight ]:
478.61

Related Compounds

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