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Oleoyl Coenzyme A

Names

[ CAS No. ]:
1716-06-9

[ Name ]:
Oleoyl Coenzyme A

[Synonym ]:
<U-14C>-Oleyl-CoA
Oleoyl coenzyme A
S-octadec-9c-enoyl-coenzyme-A
Oleyl coenzyme A
S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-octadec-9-enethioate
cis-9-Octadecenoyl-CoA
S-oleoylcoenzyme A
Oleyl-CoA

Biological Activity

[Description]:

Oleoyl coenzyme A (Oleoyl-CoA) is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A has a role as an Escherichia coli metabolite and a mouse metabolite[1][2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Oleoyl coenzyme A (1 μM) can activate sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 in Xenopus oocytes[2].

[References]

[1]. Regina Ensenauer, et al. Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids. J Biol Chem. 2005 Sep 16;280(37):32309-16.  

[2]. F M Gribble, et al. Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA. J Biol Chem. 1998 Oct 9;273(41):26383-7.  

Chemical & Physical Properties

[ Density]:
1.51g/cm3

[ Molecular Formula ]:
C39H68N7O17P3S

[ Molecular Weight ]:
1031.98

[ Exact Mass ]:
1031.36000

[ PSA ]:
418.36000

[ LogP ]:
6.06520

[ Index of Refraction ]:
1.626

Related Compounds