Agitoxin 2

Names

[ CAS No. ]:
168147-41-9

[ Name ]:
Agitoxin 2

Biological Activity

[Description]:

Agitoxin-2 is a K+ channel inhibitor, with IC50 values of 201 pM and 144 pM for mKV1.3 and mKV1.1, respectively)[1][2].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[References]

[1]. M L Garcia, et al. Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry. 1994 Jun 7;33(22):6834-9.

[2]. Raveendra Anangi, et al. Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockers.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆₉H₂₇₈N₅₄O₄₈S₈

[ Molecular Weight ]:
4090.87

Related Compounds

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