fluphenazine sulfoxide

[ Density]:
1.43g/cm3

[ Boiling Point ]:
615.4ºC at 760mmHg

[ Melting Point ]:
131-133ºC

[ Molecular Formula ]:
C₂₂H₂₆F₃N₃O₂S

[ Molecular Weight ]:
453.52100

[ Flash Point ]:
326ºC

[ Exact Mass ]:
453.17000

[ PSA ]:
66.23000

[ LogP ]:
4.13010

[ Vapour Pressure ]:
5.28E-16mmHg at 25°C

[ Index of Refraction ]:
1.654

[ Storage condition ]:
2-8°C

Plasma levels of fluphenazine in patients receiving fluphenazine decanoate. Relationship to clinical response.

Br. J. Psychiatry 158 , 658-65, (1991)

The levels of fluphenazine and fluphenazine sulphoxide in schizophrenic patients who were randomly assigned to receive either 5 mg or 25 mg of fluphenazine decanoate every two weeks were monitored. Pa...

Impact of clinical pharmacokinetics on neuroleptic therapy in patients with schizophrenia.

J. Psychiatry Neurosci. 19(4) , 254-64, (1994)

This review covers some recent work on: 1. The effects of route of administration on the pharmacokinetics of fluphenazine and some of its metabolites; 2. The clinical pharmacokinetics of fluphenazine ...

The sulfoxidation of fluphenazine in schizophrenic patients maintained on fluphenazine decanoate.

Psychopharmacology 93(3) , 369-73, (1987)

Highly sensitive radioimmunoassays were applied to study the sulfoxidation of fluphenazine in 30 schizophrenic patients maintained on either 5 mg or 25 mg fluphenazine decanoate by intramuscular injec...

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