AGN 192870

Names

[ Name ]:
AGN 192870

Biological Activity

[Description]:

AGN 192870 is a RAR neutral antagonist with Kds of 147, 33, and 42 nM for RARα, RARβ, and RARγ, respectively. AGN 192870 shows IC50s of 87 and 32 nM for RARαand RARγ, respectively. AGN 192870 shows RARβ partial agonism[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR

[References]

[1]. Klein ES, et al. Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists. J Biol Chem. 1996;271(37):22692-22696.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₂O₂

[ Molecular Weight ]:
378.46

AGN 192870

Names

Biological Activity

Chemical & Physical Properties

Related Compounds