Fosenazide
Names
[ CAS No. ]:
16543-10-5
[ Name ]:
Fosenazide
[Synonym ]:
Hydifen
Diphenylphosphinyl acethydrazide
2-(Diphenylphosphoryl)acetohydrazide
Phosphabenzide
Fosenazide
diphenylphosphinoacetic acid hydrazide
diphenylphosphinoylacetic hydrazide
ACETIC ACID,(DIPHENYLPHOSPHINYL)-,HYDRAZIDE
Fosenazidum [INN-Latin]
Fosenazida [INN-Spanish]
diphenylphosphorylacetic acid hydrazide
diphenylphosphinylacetic acid hydrazide
Gidifen
Chemical & Physical Properties
[ Density]:
1.26g/cm3
[ Boiling Point ]:
477.4ºC at 760mmHg
[ Molecular Formula ]:
C14H15N2O2P
[ Molecular Weight ]:
274.25500
[ Flash Point ]:
242.5ºC
[ Exact Mass ]:
274.08700
[ PSA ]:
85.49000
[ LogP ]:
2.53100
[ Vapour Pressure ]:
2.8E-09mmHg at 25°C
[ Index of Refraction ]:
1.604
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AH3293000
- CHEMICAL NAME :
- Acetic acid, (diphenylphosphinyl)-, hydrazide
- CAS REGISTRY NUMBER :
- 16543-10-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H15-N2-O2-P
- MOLECULAR WEIGHT :
- 274.28
- WISWESSER LINE NOTATION :
- ZMV1PO&R&R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 315 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 20,315,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 293 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2751389
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 315 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic Behavioral - analgesia
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 43,122,1980
Safety Information
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%