1,3-Bis[(2H3)methyloxy]benzene

Names

[ CAS No. ]:
16469-85-5

[ Name ]:
1,3-Bis[(2H3)methyloxy]benzene

[Synonym ]:
1,3-bis-tert-butylsulfanyl-propane
1,3-Bis-tert-butylmercapto-propan
2,2,8,8-Tetramethyl-3,7-dithianonan
Di-tert.-butylthio-1.3-propan
1.3-Bis-<tert-butyl-thio>-propan
1,3-bis-trideuteriomethoxybenzene
1,3-Bis[(H)methyloxy]benzene
Benzene, 1,3-bis(methyl-d-oxy)-

Biological Activity

[Description]:

1,3-Dimethoxybenzene-d6 is the deuterium labeled 1,3-Dimethoxybenzene[1]. 1,3-Dimethoxybenzene belongs to the class of organic compounds known as dimethoxybenzenes. 1,3-Dimethoxybenzene is an intermediate in synthesis of organic compounds[2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Gregory Michael Shutske, et al. Process for the preparation of 2-chloro-1,3-dimethoxybenzene. EP0067342A1

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
217.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H4D6O2

[ Molecular Weight ]:
144.201

[ Flash Point ]:
87.8±0.0 °C

[ Exact Mass ]:
144.105743

[ PSA ]:
18.46000

[ LogP ]:
1.93

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.488

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds