MmpL3-IN-3

Names

[ Name ]:
MmpL3-IN-3

Biological Activity

[Description]:

MmpL3-IN-3 (Compound 12) is a MmpL3 inhibitor. MmpL3-IN-3 shows a MIC of 0.1 μM against H37Rv. MmpL3-IN-3 shows good stability in mouse liver microsomes. MmpL3-IN-3 can be used for anti-tubercular research[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Vasudevan N, et al. Synthesis, biological evaluation and docking studies of silicon incorporated diarylpyrroles as MmpL3 inhibitors: An effective strategy towards development of potent anti-tubercular agents. Eur J Med Chem. 2023 Jul 16;259:115633.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₃ClN₂Si

[ Molecular Weight ]:
437.09

Related Compounds

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