CC-90003

Names

[ CAS No. ]:
1621999-82-3

[ Name ]:
CC-90003

Biological Activity

[Description]:

CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity.

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> ERK

Signaling Pathways >> Stem Cell/Wnt >> ERK

Research Areas >> Cancer

[Target]

ERK1

ERK2

[In Vitro]

CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity[1].

[References]

[1]. Monica M. Mita, et al. A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors. Journal of Clinical Oncology 35, no. 15_suppl (May 20 2017) 2577-2577.

[Related Small Molecules]

SCH772984 | Ravoxertinib | Honokiol | Sodium tauroursodeoxycholate | LY3214996 | Ulixertinib (BVD-523) | TIC10 | Astragaloside IV | XMD8-92 | LM22B 10 | VX-11e | FR 180204 | Mogrol | Pluripotin | AX 15836

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₁F₃N₆O₂

[ Molecular Weight ]:
458.44

[ Storage condition ]:
-20℃

Related Compounds

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