1621999-82-3

1621999-82-3 structure

Name: CC-90003
Chemical Name: CC-90003
CAS Number: 1621999-82-3
Molecular Formula: C₂₂H₂₁F₃N₆O₂
Molecular Weight: 458.44
Catalog: Signaling Pathways MAPK/ERK Pathway ERK
Create Date: 2018-09-30 21:17:36
Modify Date: 2025-08-26 13:34:04
CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity.

Name	CC-90003

Description	CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity.
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK Research Areas >> Cancer
Target	ERK1 ERK2
In Vitro	CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity[1].
References	[1]. Monica M. Mita, et al. A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors. Journal of Clinical Oncology 35, no. 15_suppl (May 20 2017) 2577-2577.