NSC636819

Names

[ Name ]:
NSC636819

[Synonym ]:
Benzene, 1,5-bis[(E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitro-
1,5-Bis[(E)-2-(3,4-dichlorophenyl)vinyl]-2,4-dinitrobenzene
1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene

Biological Activity

[Description]:

NSC636819 is a competitive and selective inhibitor of KDM4A/KDM4B. KDM4A/KDM4B are potential progression factors for prostate cancer. NSC636819 has the potential for the research of cancer diseases, especially prostate cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Demethylase

[References]

[1]. Chu CH, et al. KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor. J Med Chem. 2014;57(14):5975-5985.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
625.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₂H₁₂Cl₄N₂O₄

[ Molecular Weight ]:
510.15

[ Flash Point ]:
332.1±31.5 °C

[ Exact Mass ]:
507.955109

[ LogP ]:
8.59

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.753

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.