1618672-71-1

1618672-71-1 structure

Name: NSC636819
Chemical Name: NSC 636819
CAS Number: 1618672-71-1
Molecular Formula: C₂₂H₁₂Cl₄N₂O₄
Molecular Weight: 510.15
Create Date: 2022-03-26 21:50:36
Modify Date: 2025-09-23 10:21:56
NSC636819 is a competitive and selective inhibitor of KDM4A/KDM4B. KDM4A/KDM4B are potential progression factors for prostate cancer. NSC636819 has the potential for the research of cancer diseases, especially prostate cancer[1].

Name	NSC 636819
Synonyms	Benzene, 1,5-bis[(E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitro- 1,5-Bis[(E)-2-(3,4-dichlorophenyl)vinyl]-2,4-dinitrobenzene 1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene

Description	NSC636819 is a competitive and selective inhibitor of KDM4A/KDM4B. KDM4A/KDM4B are potential progression factors for prostate cancer. NSC636819 has the potential for the research of cancer diseases, especially prostate cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Demethylase
References	[1]. Chu CH, et al. KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor. J Med Chem. 2014;57(14):5975-5985.