2’,3’,5’-Tri-O-acetyl-5-methoxycarbonylmethyl-2-thiouridine

Names

[ CAS No. ]:
1613530-52-1

[ Name ]:
2’,3’,5’-Tri-O-acetyl-5-methoxycarbonylmethyl-2-thiouridine

Biological Activity

[Description]:

2’,3’,5’-Tri-O-acetyl-5-methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C18H22N2O10S

[ Molecular Weight ]:
458.44

Related Compounds

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