BAY-1316957

Names

[ Name ]:
BAY-1316957

Biological Activity

[Description]:

BAY-1316957 is a highly potent and selective EP4 receptor antagonist with an IC50 of 15.3 nM. Good oral bioavailability[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

Research Areas >> Inflammation/Immunology

[Target]

IC50: 15.3 nM (EP4)[1]

[References]

[1]. Bäurle S, et al. Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis. J Med Chem. 2019 Mar 14;62(5):2541-2563.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₇N₃O₃

[ Molecular Weight ]:
441.52

Related Compounds

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