4-[4-(2-hydroxyethyl)piperazin-1-yl]butane-1-sulfonic acid

Names

[ Name ]:
4-[4-(2-hydroxyethyl)piperazin-1-yl]butane-1-sulfonic acid

[Synonym ]:
4-(2-HYDROXYETHYL)-1-PIPERAZINEBUTANESULFONIC ACID
HEPBS
N-(2-Hydroxyethyl)piperazine-N'-(4-butanesulfonic acid)
1-Piperazinebutanesulfonic acid, 4-(2-hydroxyethyl)-
4-(4-(2-Hydroxyethyl)piperazin-1-yl)butane-1-sulfonic acid
4-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-butanesulfonic acid

Biological Activity

[Description]:

HEPBS is a zwitterionic buffering agent with a pH range (7.6-9.0) similar to that of biological systems. HEPBS can be used in the culture of cells[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. N Roy L, et al. Buffer Standards for the Physiological pH of N-(2-Hydroxyethyl) piperazine-N'-4-butanesulfonic Acid (HEPBS) from 5 to 55 C. The Open Electrochemistry Journal, 2012, 4(1).

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C₁₀H₂₂N₂O₄S

[ Molecular Weight ]:
266.358

[ Exact Mass ]:
266.130035

[ PSA ]:
89.46000

[ LogP ]:
-2.16

[ Index of Refraction ]:
1.532

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

[ HS Code ]:
2933599090

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

New zwitterionic butanesulfonic acids that extend the alkaline range of four families of Good buffers: evaluation for use in biological systems.

J. Biochem. Biophys. Methods 37 , 117, (1998)

Four new zwitterionic butanesulfonic acid buffers that are structurally related to four families of Good buffers were evaluated for use in biological systems. These buffers, with pKa values from 7.6 t...