MC-VC-PAB-Cyclohexanediamine-Thailanstatin A

Names

[ CAS No. ]:
1609108-96-4

[ Name ]:
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A

Biological Activity

[Description]:

MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a Spliceostatin (HY-16466) analog, and a drug-linker conjugates for ADC, consisting of ADC Cytotoxin Thailanstatin A (HY-129589) and cleavable ADC linker (MC-vc-PAB). MC-VC-PAB-Cyclohexanediamine-Thailanstatin A can be used for ADC synthesis[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Dirico KJ, et al. Preparation of spliceostatin analog antibody conjugates for cancer treatment. World Intellectual Property Organization, WO2014068443 A1. 2014-05-08.

Chemical & Physical Properties

[ Molecular Formula ]:
C63H91N9O16

[ Molecular Weight ]:
1230.45

Related Compounds

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