DMP 543
Names
Biological Activity
[Description]:
DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer[1][2].
[Related Catalog]:
[Target]
KV7 channel
[In Vitro]
DMP-543 enhances [3H]ACh release from rat brain slices, with an EC50 of 700 nM[2].
[References]
Chemical & Physical Properties
[ Density]:
1.319g/cm3
[ Boiling Point ]:
593.1ºC at 760mmHg
[ Molecular Formula ]:
C26H18F2N2O
[ Molecular Weight ]:
412.43
[ Flash Point ]:
312.5ºC
[ Exact Mass ]:
412.13900
[ PSA ]:
42.85000
[ LogP ]:
5.07070
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.643