8-Hydroxybergapten

Names

[ Name ]:
8-Hydroxybergapten

[Synonym ]:
9-hydroxy-4-methoxy-furo[3,2-g]chromen-7-one
5-methoxypsoralin
8-hydroxy-5-methoxypsoralen
7H-Furo(3,2-g)(1)benzopyran-7-one,9-hydroxy-4-methoxy
7H-Furo[3,2-g][1]benzopyran-7-one, 9-hydroxy-4-methoxy-
8-Hydroxybergapten
9-Hydroxy-4-methoxy-7H-furo[3,2-g]chromen-7-one
InChI=1/C12H8O5/c1-15-10-6-2-3-8(13)17-12(6)9(14)11-7(10)4-5-16-11/h2-5,14H,1H3
9-hydroxy-4-methoxypsoralen
5-methoxy-8-hydroxypsoralen
MVJHUMZXIJPVHV-UHFFFAOYSA
7H-Furo(3,2-g)(1)benzopyran-7-one, 9-hydroxy-4-methoxy-

Biological Activity

[Description]:

8-hydroxybergapten is O-methylated by cell-free extracts of Ruta cells to isopimpinellin, in reactions mediated by discrete O-methyltransferases. 8-hydroxybergapten has excellent anti-wrinkle effect[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Brown SA, et al. The biosynthesis of isopimpinellin. Can J Biochem. 1977 Jul;55(7):686-92.

[2]. Mu-Hyun Jin, et al. Composition for promoting synthesis of collagen, and composition for external preparation for skin comprising the same.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
488.2±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₈O₅

[ Molecular Weight ]:
232.189

[ Flash Point ]:
249.1±28.7 °C

[ Exact Mass ]:
232.037170

[ PSA ]:
72.81000

[ LogP ]:
0.96

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.670

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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