m-PEG3-CH2COOH

Names

[ Name ]:
m-PEG3-CH2COOH

[Synonym ]:
(monomethoxy)triethylene glycol acetic acid
2-(2-(2-methoxyethoxy)-ethoxy)-ethoxy-acetic acid
3,6,9,12-tetraoxatridecanoic acid
CH3O-TEG acetic acid
2,5,8,11-Tetraoxatridecan-13-oic acid

Biological Activity

[Description]:

m-PEG3-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Chen X, et al. Histidine-Specific Peptide Modification via Visible-Light-Promoted C-H Alkylation. J Am Chem Soc. 2019 Nov 13;141(45):18230-18237.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₈O₆

[ Molecular Weight ]:
222.23600

[ Exact Mass ]:
222.11000

[ PSA ]:
74.22000

Safety Information

[ Hazard Codes ]:
Xi

m-PEG3-CH2COOH

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Related Compounds