Methyl homoveratrate

Names

[ Name ]:
Methyl homoveratrate

[Synonym ]:
Acetic acid, (3,4-dimethoxyphenyl)-, methyl ester
Benzeneacetic acid, 3,4-dimethoxy-, methyl ester
Methyl (3,4-dimethoxyphenyl)acetate
methyl 2-(3,4-dimethoxyphenyl)acetate

Biological Activity

[Description]:

Methyl homoveratrate, a metabolite of RWJ-26240 in vivo, can be identified in plasma, urine and faecal extract. McN5691 (RWJ-26240) is a voltage-sensitive calcium channel blocker[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Cardiovascular Disease

[References]

[1]. Wu WN, et al. Biotransformation of an antihypertensive arylalkylamine analogue in the rat. Xenobiotica. 1998 Oct;28(10):957-72.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
285.4±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₄O₄

[ Molecular Weight ]:
210.227

[ Flash Point ]:
121.6±23.2 °C

[ Exact Mass ]:
210.089203

[ PSA ]:
44.76000

[ LogP ]:
1.70

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.496

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%