MK 386

Names

[ CAS No. ]:
158493-17-5

[ Name ]:
MK 386

Biological Activity

[Description]:

MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> 5 alpha Reductase

[Target]

5-α-reductase I[1]


[References]

[1]. Bühler P, et al. Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors. Urol Int. 2010;84(2):203-11.  

Chemical & Physical Properties

[ Density]:
0.951g/cm3

[ Boiling Point ]:
505.2ºC at 760mmHg

[ Molecular Formula ]:
C28H49NO

[ Molecular Weight ]:
415.69

[ Flash Point ]:
203.9ºC

[ Exact Mass ]:
415.38100

[ PSA ]:
20.31000

[ LogP ]:
7.11230

[ Vapour Pressure ]:
2.48E-10mmHg at 25°C

[ Index of Refraction ]:
1.494

Related Compounds