Bectumomab

Names

[ Name ]:
Bectumomab

Biological Activity

[Description]:

Bectumomab (IMMU-LL 2) is an humanized IgG2a mAb against human CD22 (antigen). Bectumomab is also an anti-lymphoma antibody fragment. Bectumomab can be used for imaging in combination with technetium 99 (Tc99m LL2 Fab). Moreover, Bectumomab examines in the staging of recurrent or newly diagnosed non-Hodgkin's lymphoma (NHL) and to assess targeting before radioimmunotherapy (RIT)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

CD22[1]

[In Vitro]

Bectumomab 可与小鼠单克隆免疫球蛋白 LL-2 轻链二硫化形成二聚体[1]。

[References]

[1]. Lamonica D, et al. Radioimmunoscintigraphy (RIS) with bectumomab (Tc99m labeled IMMU-LL2, Lymphoscan) in the assessment of recurrent non-Hodgkin's lymphoma (NHL). Cancer Biother Radiopharm. 2002 Dec;17(6):689-97.

Chemical & Physical Properties

No Any Chemical & Physical Properties