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BOS172722

Names

[ CAS No. ]:
1578245-44-9

[ Name ]:
BOS172722

Biological Activity

[Description]:

BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Mps1
Signaling Pathways >> Cytoskeleton >> Mps1
Research Areas >> Cancer

[Target]

2 nM (MPS1)[1].


[In Vitro]

BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM. BOS-172722 also has potential for the treatment of various forms of breast cancer[1].

[References]

[1]. ARYL SULFONOHYDRAZIDES. WO 2014037750 A1.


[Related Small Molecules]

CFI402257 | BAY1217389 | BAY 1161909 | NMS-P715 | AZ 3146 | MPI-0479605 | Mps1-IN-1 | Mps1-IN-2 | Mps1-IN-3 | CCT251455

Chemical & Physical Properties

[ Molecular Formula ]:
C24H30N8O

[ Molecular Weight ]:
446.55

[ Storage condition ]:
2-8℃


Related Compounds