Clemastine

Names

[ Name ]:
Clemastine

[Synonym ]:
MFCD00137486
clemastinum
EINECS 239-055-2
clemastine

Biological Activity

[Description]:

Clemastine (HS-592) is a potent and orally active histamine receptor H1 antagonist. Clemastine is an antihistamine mainly used for relieving symptoms of allergic reactions primarily by competing with histamine to bind H1 receptors. Anti-inflammatory effects[1][2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

[References]

[1]. Clemastine. In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; January 16, 2017.

Chemical & Physical Properties

[ Density]:
1.097 g/cm3

[ Boiling Point ]:
425.2ºC at 760mmHg

[ Molecular Formula ]:
C₂₁H₂₆ClNO

[ Molecular Weight ]:
343.89000

[ Flash Point ]:
211ºC

[ Exact Mass ]:
343.17000

[ PSA ]:
12.47000

[ LogP ]:
5.04230

[ Index of Refraction ]:
1.553

Related Compounds

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