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Pseudouridimycin

Names

[ CAS No. ]:
1566586-52-4

[ Name ]:
Pseudouridimycin

Biological Activity

[Description]:

Pseudouridimycin (PUM), an antibiotic, is a selective bacterial RNA polymerase (RNAP) inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Rosenqvist P, et al. Characterization of C-nucleoside Antimicrobials from Streptomyces albus DSM 40763: Strepturidin is Pseudouridimycin. Sci Rep. 2019 Jun 20;9(1):8935.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H25N7O10

[ Molecular Weight ]:
487.42

[ Storage condition ]:
-20°C

Related Compounds