HS-27

Names

[ CAS No. ]:
1562024-11-6

[ Name ]:
HS-27

Biological Activity

[Description]:

Hs-27 is a Novel Hsp90 Inhibitor, Exhibits Diagnostic and Therapeutic Potential in Triple Negative Breast Cancer.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> HSP

Signaling Pathways >> Cell Cycle/DNA Damage >> HSP

[Target]

HSP90

[In Vitro]

HS-27 labels all receptor subtypes of breast cancer, but not normal cells, and specifically binds to Hsp90 expressed on the surface of breast cancer cells before being internalized. HS-27 fluorescence is greater in tumor than non-tumor tissue[1].

[References]

[1]. Crouch BT, et al. Exploiting heat shock protein expression to develop a non-invasive diagnostic tool for breast cancer. Sci Rep. 2019 Mar 5;9(1):3461.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₂H₆₀N₆O₁₂S

[ Molecular Weight ]:
992.4

HS-27

Names

Biological Activity

Chemical & Physical Properties

Related Compounds