4-(Phenyldiazenyl)benzoic acid

Names

[ Name ]:
4-(Phenyldiazenyl)benzoic acid

[Synonym ]:
MFCD00020348
4-Phenylazobenzoic acid
EINECS 216-347-8
Azobenzene-4-carboxylic Acid

Biological Activity

[Description]:

4-(Phenyldiazenyl)benzoic acid is a photosensitive and photoswitchable TRPA1 agonist that can be used as pharmacological tools for study of pain signaling.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Others

[References]

[1]. Qiao Z, et al. Photosensitive and Photoswitchable TRPA1 Agonists Optically Control Pain through Channel Desensitization. J Med Chem. 2021 Nov 11;64(21):16282-16292.

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
418.1ºC at 760mmHg

[ Melting Point ]:
247-250ºC(lit.)

[ Molecular Formula ]:
C₁₃H₁₀N₂O₂

[ Molecular Weight ]:
226.23

[ Flash Point ]:
206.7ºC

[ Exact Mass ]:
226.07400

[ PSA ]:
62.02000

[ LogP ]:
3.80020

[ Vapour Pressure ]:
9.72E-08mmHg at 25°C

[ Index of Refraction ]:
1.606

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Complete ON/OFF photoswitching of the motility of a nanobiomolecular machine.

ACS Nano 8(5) , 4157-65, (2014)

To apply motor proteins as natural nanomolecular machines to transporting systems in nanotechnology, complete temporal control over ON/OFF switching of the motility is necessary. We have studied the p...

Azobenzene-Functionalised Core Cross-Linked Star Polymers and their Host-Guest Interactions. Tan S, et al.

Aust. J. Chem. 67(1) , 173-178, (2014)

New dyes for solar cells based on nanostructured semiconducting metal oxides: Synthesis and characterisation of ruthenium (II) complexes with thiol-substituted ligands. Ohlsson J, et al.

J. Photochem. Photobiol. A: Chem. 148(1) , 41-48, (2002)