2,4-Diaminopyrimidine

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
401.7±37.0 °C at 760 mmHg

[ Melting Point ]:
143-147 °C(lit.)

[ Molecular Formula ]:
C₄H₆N₄

[ Molecular Weight ]:
110.117

[ Flash Point ]:
225.6±13.7 °C

[ Exact Mass ]:
110.059242

[ PSA ]:
77.82000

[ LogP ]:
-0.64

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.695

[ Storage condition ]:
Refrigerator (+4°C)

[ Water Solubility ]:
840 g/L (25 ºC)

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2942000000

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Nitric oxide (NO) is involved in desensitization of μ-opioid receptors (MOR). We used extracellular recordings in vitro to unmask the NO-dependent pathways involved in MOR desensitization in the rat l...

Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents.

Eur. J. Med. Chem. 96 , 269-80, (2015)

Therapeutics of metastatic or triple-negative breast cancer are still challenging in clinical. Herein we demonstrated the design and optimization of a series of hybrid of 2,4-diaminopyrimidine and ary...

Cocrystals of 6-methyl-2-thiouracil: presence of the acceptor-donor-acceptor/donor-acceptor-donor synthon.

Acta Crystallogr. C Struct. Chem. 71(Pt 3) , 229-38, (2015)

The results of seven cocrystallization experiments of the antithyroid drug 6-methyl-2-thiouracil (MTU), C(5)H(6)N(2)OS, with 2,4-diaminopyrimidine, 2,4,6-triaminopyrimidine and 6-amino-3H-isocytosine ...

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