PD 151,242
Names
[ CAS No. ]:
155561-67-4
[ Name ]:
PD 151,242
[Synonym ]:
N-((Hexahydro-1-azepinyl)carbonyl)-leu(1-methyl)-trp-trp
N-(N-(N-((Hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-D-tyrosine
N-[N-[N-[(Hexahydro-1H-azepin-1-yl)carbonyl]-L-leucyl]-1-methyl-D-tryptophyl]-D-tyrosine
PD 151,242
N-((Hexahydro-1-azepinyl)carbonyl)-leucyl(1-methyl)-tryptophyl-tryptophan
Chemical & Physical Properties
[ Density]:
1.28g/cm3
[ Boiling Point ]:
976.8ºC at 760mmHg
[ Molecular Formula ]:
C34H45N5O6
[ Molecular Weight ]:
619.75100
[ Flash Point ]:
544.5ºC
[ Exact Mass ]:
619.33700
[ PSA ]:
163.47000
[ LogP ]:
5.54650
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.627
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
Nat. Protoc. 2 , 1288-96, (2007)
A nearly quantitative 18-component synthesis of a nanocontainer, which is built up from six bowl-shaped cavitands that are connected together with 12 -CH=N-CH2CH2-N=CH- linkers, and its subsequent red...
Endothelin-1[1-31], acting as an ETA-receptor selective agonist, stimulates proliferation of cultured rat zona glomerulosa cells.FEBS Lett. 487(2) , 194-8, (2000)
Endothelin-1 (ET-1)[1-31] is a novel hypertensive peptide that mimics many of the vascular effects of the classic 21 amino acid peptide ET-1[1-21]. However, at variance with ET-1[1-21] that enhances a...
Comparison of endothelin-A and endothelin-B receptor distribution visualized by radioligand binding versus immunocytochemical localization using subtype selective antisera.J. Cardiovasc. Pharmacol. 44 Suppl 1 , S224-6, (2004)
Molecular studies have predicted the existence in human tissue of splice variants and modifications to the amino acid sequence of endothelin receptors that may modulate function. Endothelin-A (ETA) re...