MeDTC

Names

[ Name ]:
MeDTC

[Synonym ]:
N,N-diethylthiocarbamate methyl sulfone
S-Methyl-N,N-diethylthiocarbamate Sulfone
S-methyl N,N-diethylthiolcarbamate sulfone
N,N-diethyl-1-methylsulfonyl-formamide
MeDTC

Biological Activity

[Description]:

MeDTC (S-Methyl-N,N-diethylthiocarbamate Sulfone), a Disulfiram metabolite, is a potent, irreversible aldehyde dehydrogenase (ALDH) inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Aldehyde Dehydrogenase (ALDH)

Research Areas >> Metabolic Disease

[References]

[1]. D C Mays, et al. S-methyl N,N-diethylthiocarbamate sulfone, a potential metabolite of disulfiram and potent inhibitor of low Km mitochondrial aldehyde dehydrogenase. Biochem Pharmacol. 1995 Mar 1;49(5):693-700.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₁₃NO₃S

[ Molecular Weight ]:
179.24

[ Exact Mass ]:
179.06200

[ PSA ]:
62.83000

[ LogP ]:
1.57360

MeDTC

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds