11α-O-Tigloyl-12β-O-acetyltenacigenin B

Names

[ Name ]:
11α-O-Tigloyl-12β-O-acetyltenacigenin B

Biological Activity

[Description]:

11α-O-Tigloyl-12β-O-acetyltenacigenin B is an ester derivative of Tenacigenin B (HY-N1168), which is isolated from Garcinia cambogia (MTC). Tenacigenin B modulates the antitumor effects of Aurora-A in lymphoma.

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Aurora Kinase

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Aurora Kinase

[References]

[1]. Zhu RJ, et al.Total aglycones from Marsdenia tenacissima increases antitumor efficacy of paclitaxel in nude mice. Molecules. 2014 Sep 5;19(9):13965-75.

[2]. Dai X, et al.Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study. Med Sci Monit. 2019 Sep 1;25:6563-6573.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₄₀O₇

[ Molecular Weight ]:
488.61

Related Compounds

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