Cartap

Names

[ Name ]:
Cartap

[Synonym ]:
S,S’-[2-(dimethylamino)-1,3-propanediyl] dicarbamothioate
Patap
S,S’-(2-dimethylaminotrimethylene) bis(thiocarbamate)
thiobel
S,S'-[2-(Dimethylamino)-1,3-propanediyl] dicarbamothioate
Carbamothioic acid, S,S'-[2-(dimethylamino)-1,3-propanediyl] ester
Dihydronereistoxin dicarbamate
S,S'-[2-(Dimethylamino)-1,3-propandiyl]bis(thiocarbamat)
S,S’-[2-(dimethylamino)propane-1,3-diyl] dicarbamothioate
1,3-Bis(carbamoylthio)-2-N,N-(dimethylamino)propane
Cartap
sanvex
1,3-bis(carbamoylthio)-2-(N,N-dimethylamino)propane
S,S'-[2-(Dimethylamino)-1,3-propanediyl] bis(carbamothioate)
TL-1258
UNII-Z45YUY784H
S,S'-[2-(Dimethylamino)propane-1,3-diyl] dicarbamothioate
S,S'-[2-(Dimethylamino)propan-1,3-diyl]bis(thiocarbamat)
Vegetox
SS2DIMETHYLAMINO13PROPANEDIYLDITHIOCARBAMATE
t-1258

Biological Activity

[Description]:

Cartap is an organonitrogen insecticide, can cause a marked irreversible Ca2+-dependent contracture in both isolated mouse and rabbit phrenic nerve-diaphragms[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Cartap (10-1000 μM; 24 hours) exerts a dose- and time-dependent cytotoxic effect in C2C12 cells. Cartap significantly increases the level of endogenous reactive oxygen species (ROS) in C2C12 cells in a dose- and time-dependent manner[1].

[References]

[1]. Jiunn-Wang Liao, et al. Cartap-induced cytotoxicity in mouse C2C12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects. Toxicology. 2006 Feb 15;219(1-3):73-84.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
407.2±55.0 °C at 760 mmHg

[ Melting Point ]:
-80ºC

[ Molecular Formula ]:
C₇H₁₅N₃O₂S₂

[ Molecular Weight ]:
237.343

[ Flash Point ]:
200.1±31.5 °C

[ Exact Mass ]:
237.060562

[ PSA ]:
140.02000

[ LogP ]:
0.53

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.591

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FD1220000

CHEMICAL NAME :: Carbamic acid, thio-, S,S'-(2-(dimethylamino)trimethylene) ester

CAS REGISTRY NUMBER :: 15263-53-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H15-N3-O2-S2

MOLECULAR WEIGHT :: 237.37

WISWESSER LINE NOTATION :: ZVS1Y1SVZN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 225 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 14,109,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 92 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 34,935,1970

Safety Information

[ Hazard Codes ]:
N: Dangerous for the environment;

[ Risk Phrases ]:
R50/53

[ Safety Phrases ]:
60-61

[ HS Code ]:
2930909054

Customs

[ HS Code ]: 2930200011

[ Summary ]:
2930200011 s,s'-(2-(dimethylamino)propane-1,3-diyl) dicarbamothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

Related Compounds

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