ω-Grammotoxin SIA

Names

[ Name ]:
ω-Grammotoxin SIA

Biological Activity

[Description]:

ω-Grammotoxin SIA (GrTx) is P/Q and N-type voltage-gated Calcium channels inhibitor. ω-Grammotoxin SIA is also a protein toxin that can be obtained from spider venom. ω-Grammotoxin SIA has the potential to study neurological diseases as well as cardiovascular diseases[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Neurological Disease

[References]

[1]. Takeuchi K, et al. Solution structure of omega-grammotoxin SIA, a gating modifier of P/Q and N-type Ca(2+) channel. J Mol Biol. 2002 Aug 16;321(3):517-26.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇₇H₂₆₃N₅₃O₄₉S₆

[ Molecular Weight ]:
4109.70

[ Storage condition ]:
−20°C

[ Water Solubility ]:
aqueous buffer: soluble

Safety Information

[ WGK Germany ]:
3

Related Compounds

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