5',5-Difluoro BAPTA tetrapotassium

Names

[ Name ]:
5',5-Difluoro BAPTA tetrapotassium

Biological Activity

[Description]:

5,5'-Difluoro BAPTA tetrapotassium is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA tetrapotassium shows large 19F NMR chemical shifts upon chelating divalent cations. 5,5'-Difluoro BAPTA tetrapotassium has high selectivity for Ca2+. 5,5'-Difluoro BAPTA tetrapotassium can inhibit the growth of pollen tube[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Fe2+ ion concentrations were measured following addition of 5 mM 5,5'-Difluoro BAPTA tetrapotassium to the culture medium. Fe2+ forms a complex with 5,5'-Difluoro BAPTA tetrapotassium (Kd=50 nM) that exhibits a characteristic peak down-field from biological ions such as Ca2+ and Zn2+[3].

[References]

[1]. Bar-Shir A, et al. Metal ion sensing using ion chemical exchange saturation transfer 19F magnetic resonance imaging. J Am Chem Soc. 2013 Aug 21;135(33):12164-7.

[2]. Pierson ES, et al. Pollen tube growth is coupled to the extracellular calcium ion flux and the intracellular calcium gradient: effect of BAPTA-type buffers and hypertonic media. Plant Cell. 1994 Dec;6(12):1815-28.

[3]. Kostellow AB, et al. Iron-catalyzed lipid peroxidation in aortic cells in vitro: protective effect of extracellular magnesium. Atherosclerosis. 2004 Jul;175(1):15-22.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₈F₂N₂O_10.4K

[ Molecular Weight ]:
664.7757264

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.