ELDKWA

Names

[ CAS No. ]:
152051-21-3

[ Name ]:
ELDKWA

Biological Activity

[Description]:

ELDKWA is the highly conserved amino acids on the ecto-domain of gp41. ELDKWA acts as the epitope of a neutralizing monoclonal antibody 2F5 (mAb 2F5)directed against human immunodeficiency virus type 1[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. T Muster, et al. Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS. J Virol. 1994 Jun;68(6):4031-4.

[2]. Y Tian, et al. Structure-affinity relationships in the gp41 ELDKWA epitope for the HIV-1 neutralizing monoclonal antibody 2F5: effects of side-chain and backbone modifications and conformational constraints. J Pept Res. 2002 Jun;59(6):264-76.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₅H₅₂N₈O₁₁

[ Molecular Weight ]:
760.83400

[ Exact Mass ]:
760.37600

[ PSA ]:
325.23000

[ LogP ]:
2.43590

Related Compounds

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