benzyloxycarbonylleucyl-leucyl-leucyl-4-methyl-coumaryl-7-amide

Names

[ CAS No. ]:
152015-61-7

[ Name ]:
benzyloxycarbonylleucyl-leucyl-leucyl-4-methyl-coumaryl-7-amide

[Synonym ]:
Zlll-mca
Z-Leu-leu-leu-4-methylcoumaryl-7-amide
Benzyloxycarbonylleucyl-leucyl-leucyl-4-methyl-coumaryl-7-amide
L-Leucinamide,N-((phenylmethoxy)carbonyl)-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)

Biological Activity

[Description]:

Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome

[References]

[1]. McNaught KS, et al. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett. 2001 Jan 19;297(3):191-4.

Chemical & Physical Properties

[ Density]:
1.174g/cm3

[ Boiling Point ]:
854.4ºC at 760mmHg

[ Molecular Formula ]:
C₃₆H₄₈N₄O₇

[ Molecular Weight ]:
648.78900

[ Flash Point ]:
470.5ºC

[ Exact Mass ]:
648.35200

[ PSA ]:
166.31000

[ LogP ]:
7.40080

[ Vapour Pressure ]:
1.63E-29mmHg at 25°C

[ Index of Refraction ]:
1.561

Related Compounds

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