xinjiachalcone A

Names

[ Name ]:
xinjiachalcone A

[Synonym ]:
(2E)-1-(4-hydroxyphenyl)-3-{2-methoxy-4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-en-1-one
4'-hydroxy-2-methoxy-4-prenyloxychalcone

Biological Activity

[Description]:

Xinjiachalcone A is an active principle of Glycyrrhiza inflata Batalin. Xinjiachalcone A shows both a low MIC and a strong bactericidal activity against H. pylori, with MIC values ranged from 12.5 to 50 µM for seventeen H. pylori strains[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

MIC: 12.5-50 µM (H. pylori)[1]

[References]

[1]. Bodet C, et al. Antibacterial activities of oxyprenylated chalcones and napthtoquinone against Helicobacter pylori. Nat Prod Commun. 2014 Sep;9(9):1299-301.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₂O₄

[ Molecular Weight ]:
338.39700

[ Exact Mass ]:
338.15200

[ PSA ]:
55.76000

[ LogP ]:
4.64190

Related Compounds

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