FINDY

Names

[ CAS No. ]:
1507367-37-4

[ Name ]:
FINDY

Biological Activity

[Description]:

FINDY is a folding intermediate-selective inhibitor of DYRK1A. FINDY can inhibit Ser97 autophosphorylation with an IC50 value of 35 μM. FINDY can be used for the research of neurological disorder[1].

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> DYRK
Research Areas >> Neurological Disease

[Target]

IC50: 35 μM (Ser97 autophosphorylation)[1]


[In Vitro]

FINDY (Compound 1) 抑制 Ser97 自磷酸化，IC50 值为 35 μM[1]。

[References]

[1]. Yuka Miyazaki, et al. Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A. Eur J Med Chem. 2022 Jan 5;227:113948.  

Chemical & Physical Properties

[ Molecular Formula ]:
C16H17NO2S2Si

[ Molecular Weight ]:
347.53

Related Compounds