L 731,735

Names

[ Name ]:
L 731,735

[Synonym ]:
N-(2-(3-Mercapto-2-aminopropylamino)-3-methylpentyl)isoleucyl-homoserine
L-Homoserine,N-(N-(2-((2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-L-isoleucyl)-,(2S-(2R*(S*),3S*))
L 731,735
Nampamp-ile-hse

Biological Activity

[Description]:

L-731735 is a selective FPTase inhibitor that can inhibit ras-dependent cell transformation. L-731735 can be used in cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Farnesyl Transferase

[References]

[1]. Kohl NE, et al. Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science. 1993 Jun 25;260(5116):1934-7.

Chemical & Physical Properties

[ Density]:
1.113g/cm3

[ Boiling Point ]:
662.6ºC at 760mmHg

[ Molecular Formula ]:
C₁₉H₄₀N₄O₄S

[ Molecular Weight ]:
420.61000

[ Flash Point ]:
354.5ºC

[ Exact Mass ]:
420.27700

[ PSA ]:
179.00000

[ LogP ]:
2.52630

[ Vapour Pressure ]:
2.24E-20mmHg at 25°C

[ Index of Refraction ]:
1.521

Related Compounds

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