149756-20-7

149756-20-7 structure

Name: L 731,735
Chemical Name: (2S)-2-[[(2S,3S)-2-[[2-[(2-amino-3-sulfanylpropyl)amino]-3-methylpentyl]amino]-3-methylpentanoyl]amino]-4-hydroxybutanoic acid
CAS Number: 149756-20-7
Molecular Formula: C₁₉H₄₀N₄O₄S
Molecular Weight: 420.61000
Catalog: Signaling Pathways Metabolic Enzyme/Protease Farnesyl Transferase
Create Date: 2017-08-03 18:45:07
Modify Date: 2025-09-08 20:40:12
L-731735 is a selective FPTase inhibitor that can inhibit ras-dependent cell transformation. L-731735 can be used in cancer research[1].

Name	(2S)-2-[[(2S,3S)-2-[[2-[(2-amino-3-sulfanylpropyl)amino]-3-methylpentyl]amino]-3-methylpentanoyl]amino]-4-hydroxybutanoic acid
Synonyms	N-(2-(3-Mercapto-2-aminopropylamino)-3-methylpentyl)isoleucyl-homoserine L-Homoserine,N-(N-(2-((2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-L-isoleucyl)-,(2S-(2R(S),3S*)) L 731,735 Nampamp-ile-hse

Description	L-731735 is a selective FPTase inhibitor that can inhibit ras-dependent cell transformation. L-731735 can be used in cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Farnesyl Transferase
References	[1]. Kohl NE, et al. Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science. 1993 Jun 25;260(5116):1934-7.