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Secretoneurin (mouse, rat) trifluoroacetate salt

Names

[ CAS No. ]:
149146-12-3

[ Name ]:
Secretoneurin (mouse, rat) trifluoroacetate salt

[Synonym ]:
(5α,6β)-17-(Cyclopropylmethyl)-3-hydroxy-6-{[(2R)-4-methylene-5-oxotetrahydro-2-furanyl]methoxy}-4,5-epoxymorphinan-14-yl acetate
(5α,6β)-17-(cyclopropylmethyl)-3-hydroxy-6-{[(2R)-4-methylidene-5-oxotetrahydrofuran-2-yl]methoxy}-4,5-epoxymorphinan-14-yl acetate
2(3H)-Furanone, 5-[[[(5α,6β)-14-(acetyloxy)-17-(cyclopropylmethyl)-4,5-epoxy-3-hydroxymorphinan-6-yl]oxy]methyl]dihydro-3-methylene-, (5R)-

Biological Activity

[Description]:

Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII). Secretoneurin, rat induces dopamine release in the rat striatum in vivo and in vitro, and it exerts a very strong chemotactic effect on monocytes and eosinophils but not on granulocytes[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Troger J, et al. Secretoneurin in the peripheral ocular innervation. Invest Ophthalmol Vis Sci. 2005 Feb;46(2):647-54.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
667.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C159H252N40O58

[ Molecular Weight ]:
3651.95

[ Flash Point ]:
357.4±31.5 °C

[ Exact Mass ]:
495.225708

[ LogP ]:
1.63

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.643

Related Compounds