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Avacincaptad pegol sodium

Names

[ CAS No. ]:
1491144-00-3

[ Name ]:
Avacincaptad pegol sodium

Biological Activity

[Description]:

Avacincaptad pegol (ARC1905) is is an anti-C5 RNA aptamer that inhibits the cleavage of complement factor 5 (C5) into C5a and C5b. Avacincaptad pegol is being used for the study of age-related macular degeneration (AMD).

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Immunology/Inflammation >> Complement System

[References]

[1]. Powers, J. P., Dairaghi, D. J., & Jaen, J. C. (2011). Advances in the Discovery of C5a Receptor Antagonists. Annual Reports in Medicinal Chemistry, 171–186.

Chemical & Physical Properties

[ Molecular Weight ]:
53500.00

Related Compounds