L-Albizziin

Names

[ Name ]:
L-Albizziin

[Synonym ]:
MFCD00007952
L-b-Ureidoalanine
L-albizziine
L-ALBIZZIIN
EINECS 216-046-1

Biological Activity

[Description]:

L-albizziin, as a sulfhydryl group reagent, is a glutamase inhibitor. L-albizziin can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Glutamase[1]

[In Vitro]

L-albizziin, as a sulfhydryl group reagent, is a glutamase inhibitor[1].

[References]

[1]. Durá MA, et al. Purification and characterisation of a glutaminase from Debaryomyces spp.. Int J Food Microbiol. 2002;76(1-2):117-126. doi:10.1016/s0168-1605(02)00024-7

Chemical & Physical Properties

[ Density]:
1.43 g/cm3

[ Boiling Point ]:
359.1ºC at 760 mmHg

[ Melting Point ]:
217°C (dec.)

[ Molecular Formula ]:
C₄H₉N₃O₃

[ Molecular Weight ]:
147.13300

[ Flash Point ]:
171ºC

[ Exact Mass ]:
147.06400

[ PSA ]:
118.44000

[ Vapour Pressure ]:
3.95E-06mmHg at 25°C

[ Index of Refraction ]:
1.55

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Molecular and genetic characterization of human cell lines resistant to L-asparaginase and albizziin.

Somat. Cell Mol. Genet. 16(1) , 59-65, (1990)

Human cell lines resistant to L-asparaginase or albizziin were isolated by multistep selection of HT1080 fibrosarcoma and MIA PaCa-2 pancreatic carcinoma cells. Mutants were cross-resistant to both dr...

Chromosomal alterations associated with overproduction of asparagine synthetase in albizziin-resistant Chinese hamster ovary cells.

Mol. Cell. Biol. 3(3) , 391-8, (1983)

The amino acid analog albizziin was used to isolate Chinese hamster ovary cell lines which overproduce asparagine synthetase. Mutants selected in a single step after ethyl methane sulfonate mutagenesi...

Use of the Escherichia coli gene for asparagine synthetase as a selective marker in a shuttle vector capable of dominant transfection and amplification in animal cells.

Mol. Cell. Biol. 7(5) , 1623-8, (1987)

A new dominant amplifiable selective system for use in bacterium-animal cell shuttle vectors was developed by the insertion of a 2-kilobase genomic fragment containing the cloned Escherichia coli gene...