N-ACETYL-TYR-VAL-LYS-ASP-AL

Names

[ Name ]:
N-ACETYL-TYR-VAL-LYS-ASP-AL

[Synonym ]:
N-Acetyl-L-tyrosyl-L-valyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-lysinamide
L-Lysinamide, N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-

Biological Activity

[Description]:

Ac-Tyr-Val-Lys-Asp-aldehyde is a caspase-1 inhibitor, can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Apoptosis >> Caspase

[Target]

Caspase-1

[References]

[1]. Mulero Mendez, et al. Caspase 1 inhibitors for the treatment of anemia: Spain, ES2769975[P]. 2020-06-29.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
976.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₆H₃₉N₅O₈

[ Molecular Weight ]:
549.617

[ Flash Point ]:
544.5±34.3 °C

[ Exact Mass ]:
549.279846

[ LogP ]:
0.43

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.554

Related Compounds

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