trans-3-Hydroxycinnamic acid

Names

[ Name ]:
trans-3-Hydroxycinnamic acid

[Synonym ]:
3-Hydroxycinnamic acid
3-(3-hydroxyphenyl)-2-Propenoate
META-COUMARICACID
m-hydroxy-Cinnamic acid
3-(3-hydroxyphenyl)acrylate
RARECHEM BK HC T323
m-Hydroxycinnamic acid
2-Propenoic acid, 3- (3-hydroxyphenyl)-
m-Hydroxycinnamic acid, trans
m-Hydroxycinnamic acid,predominantly trans
3-(3-Hydroxyphenyl)acrylsaeure
cumaric acid
EINECS 209-615-0
trans-m-Coumaric Acid
3-(3-Hydroxyphenyl)-2-propenoic acid
3-COUMARIC ACID
m-Coumaric acid
COUMARIC ACID,3
trans-3-coumaric acid
Coumaricacid
3'-Hydroxycinnamic acid
coumarinic acid
trans-3-Hydroxycinnamic acid
(2E)-3-(3-Hydroxyphenyl)acrylic acid
MFCD00004390
trans-m-Cumaric Acid
2-Propenoic acid, 3-(3-hydroxyphenyl)-, (2E)-

Biological Activity

[Description]:

(E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an aromatic acid that highly abundant in food. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an antioxidant.

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. José Teixeira, et al. Hydroxycinnamic Acid Antioxidants: An Electrochemical Overview. BioMed Research International. 2013. 18 June.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
373.2±25.0 °C at 760 mmHg

[ Melting Point ]:
193-195 °C(lit.)

[ Molecular Formula ]:
C₉H₈O₃

[ Molecular Weight ]:
164.158

[ Flash Point ]:
193.7±19.7 °C

[ Exact Mass ]:
164.047348

[ PSA ]:
57.53000

[ LogP ]:
1.83

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.660

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25-S37/39-S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918290000

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Articles

Antimicrobial activity of natural products from the flora of Northern Ontario, Canada.

Pharm. Biol. 53(6) , 800-6, (2015)

The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only ...

Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins

Bioorg. Med. Chem. 17 , 896-904, (2009)

This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoret...

Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation.

J. Agric. Food Chem. 63 , 7343-52, (2015)

Gouty inflammation results from the stimulation of monosodium urate (MSU). Interleukin-1β (IL-1β) secretion is the primary clinical manifestation of MSU attack, and MSU activates IL-1β through a nucle...