1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran

Names

[ Name ]:
1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran

[Synonym ]:
1,2,4,7,8-Dibenzofuranpentol, 3-(4-hydroxyphenyl)-, 1,2-diacetate
4,7,8-Trihydroxy-3-(4-hydroxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

Biological Activity

[Description]:

1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran, isolated from the edible mushroom Sarcodon leucopus, has antioxidant effects in the DPPH scavenging assay with the IC50 of 28 μM, inhibits malondialdehyde (MDA) with the IC50 of 71 μM, and inhibits α-glucosidase with the IC50 of 6.22 μM[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Neurological Disease

[References]

[1]. Ke Ma et al. Two sarcoviolins with antioxidative and α-glucosidase inhibitory activity from the edible mushroom Sarcodon leucopus collected in Tibet. J Nat Prod. 2014 Apr 25;77(4):942-7.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
596.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₂H₁₆O₉

[ Molecular Weight ]:
424.357

[ Flash Point ]:
314.7±30.1 °C

[ Exact Mass ]:
424.079437

[ PSA ]:
146.66000

[ LogP ]:
1.37

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.725

Safety Information

[ Hazard Codes ]:
Xi