Arachidonoyl Thio-PC

Names

[ Name ]:
Arachidonoyl Thio-PC

[Synonym ]:
2-DEOXY-2-THIOARACHIDONOYLPHOSPHATIDYLCHOLINE
(2R)-3-(Hexadecyloxy)-2-[(5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoylsulfanyl]propyl 2-(trimethylammonio)ethyl phosphate
Ethanaminium, 2-[[[(2R)-3-(hexadecyloxy)-2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]thio]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
2-DEOXY-2-THIO ARACHIDONOYL PC
1-O-hexadecyl-2-thioarachidonyl-2-deoxy-sn-glycero-3-phosphocholine
(2R)-3-(Hexadecyloxy)-2-[(5Z,8Z,11E,14E)-5,8,11,14-icosatetraenoylsulfanyl]propyl 2-(trimethylammonio)ethyl phosphate
1-Hexadecyl-2-arachidonoylthio-2-deoxy-sn-glycero-3-phosphorylcholine
1-hexadecyl-2-arachidonoylthio-2-deoxyglycero-3-phosphorylcholine
Ethanaminium, 2-[[[(2R)-3-(hexadecyloxy)-2-[[(5Z,8Z,11E,14E)-1-oxo-5,8,11,14-eicosatetraen-1-yl]thio]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
Thiopc

Biological Activity

[Description]:

Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₄H₈₂NO₆PS

[ Molecular Weight ]:
784.164

[ Exact Mass ]:
783.560059

[ PSA ]:
120.00000

[ LogP ]:
12.05

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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