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Endothelial lipase inhibitor-1

Names

[ CAS No. ]:
1466427-02-0

[ Name ]:
Endothelial lipase inhibitor-1

Biological Activity

[Description]:

Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM.

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Others >> Others

[Target]

IC50: 49 nM (Endothelial lipase)[1]


[References]

[1]. Hu CH, et al. Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3721-3725.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H22N4O4

[ Molecular Weight ]:
406.43

Related Compounds